PDGF
When cells whisper to each other, they speak in growth factors - tiny messengers of renewal and repair. Platelet-Derived Growth Factor (PDGF) is one such messenger: an innate conductor of collagen synthesis, microvascular resilience, and extracellular harmony. At Petal + Stem, we harness this molecular intelligence - not to mask the skin’s story, but to help it unfold with clarity.
Our approach honors the skin’s own rhythms. By delivering PDGF via ultrasound-guided precision, we support the subtle orchestration of healing processes - enhanced while remaining deeply natural. It’s not merely stimulation; it’s an invitation to your skin to remember its vitality.
This isn’t about visible change alone. It’s about nurturing biology that communicates with longevity - collagen rebuilding, circulation refining, a renewed capacity for resilience. In the Petal + Stem experience, each treatment becomes a dialogue between trusted science and the skin’s regenerative wisdom.
PROCEDURE LENGTH | 30–45 minutes, including preparation and post-treatment refinement.
RECOMMENDED TREATMENTS | Initial series of 2–3 treatments spaced 4–6 weeks apart, followed by maintenance every 6–12 months depending on skin condition and regenerative goals.
RESULTS | Gradual, cumulative restoration of collagen structure, improved skin texture, tone, and vascular integrity over 4–12 weeks. Optimal outcomes emerge with consistent regenerative support.
RECOVERY | Minimal. Mild swelling, redness, or pinpoint bruising may occur, typically resolving within 24–48 hours. Most patients return to normal activities the same day.
Platelet‑Derived Growth Factor (PDGF) is one of the body’s most eloquent messengers of renewal. It orchestrates collagen synthesis, encourages microvascular regeneration, and supports the cellular choreography that underlies repair and radiance.
At Petal + Stem, we elevate this native wisdom through Ariessence Pure PDGF+, a pharmaceutical‑grade, recombinant form of PDGF-BB crafted under sterile, high‑precision manufacturing. It delivers up to 300,000 times the concentration of growth factor found in traditional aesthetic formulations.
When applied post-procedure it becomes a conduit for accelerated healing. It hydrates, calms inflammation, refines texture, and deepens collagen rebuilding.
Your journey with Pure PDGF begins not with a blood draw, but with a choice for purity, potency, and predictability. Unlike traditional platelet-based therapies, Ariessence Pure PDGF requires no extraction. It arrives as a pharmaceutical-grade formulation, pre-sterilized, and meticulously dosed for consistent, high-efficacy results.
At Petal + Stem, we pair this regenerative powerhouse with advanced skin therapies designed to open microchannels, typically microneedling or laser resurfacing. These micro-injuries create a precise pathway for PDGF to penetrate deeply, delivering its healing signal directly to the dermis, where collagen synthesis and vascular repair begin.
The serum is gently infused post-treatment, soothing the skin as it accelerates repair. Many patients describe a sense of calm immediacy - redness is softened, tightness is minimized, and recovery time is noticeably reduced. Within days, the skin feels stronger, more hydrated, and visibly radiant.
Post-procedure healing | Accelerates recovery after microneedling, laser, or resurfacing by soothing inflammation and initiating deep dermal repair.
Thinning skin & crepey texture | Restores dermal density and elasticity by stimulating collagen and extracellular matrix renewal.
Fine lines & early wrinkling | Smooths subtle expression lines by enhancing structural support from within.
Redness & skin fragility | Strengthens the skin barrier and promotes microvascular repair, ideal for sensitive or rosacea-prone complexions.
Sun damage & photoaging | Encourages cellular turnover and reduces the appearance of sun-induced pigment and roughness.
Acne scarring & textural irregularities | Supports tissue remodeling for a more even, refined surface over time.
Post-inflammatory hyperpigmentation | Calms melanocyte activity and reduces pigment deposition after breakouts or trauma.
Overall skin dullness or depletion | Revitalizes tired, stressed skin by restoring hydration, tone, and regenerative function.
PDGF was designed to soothe, not stress. When used post-procedure (especially after microneedling or laser resurfacing) it becomes a natural accelerant for healing, visibly calming the skin within hours. Most patients experience only mild redness or sensitivity, which subsides quickly with the support of PDGF’s anti-inflammatory, reparative properties. At Petal + Stem, your aftercare is never left to chance. You’ll leave with precise, physician-approved guidance tailored to your treatment and skin type, so your results continue to unfold beautifully, long after the appointment ends.
True regeneration doesn’t happen overnight, it unfolds in stages, just as the skin was designed to. With Pure PDGF, many patients notice early signs of restoration within the first week: reduced redness, softened texture, and a subtle yet unmistakable radiance. Over the next 4 to 8 weeks, deeper benefits begin to surface - firmer tone, improved elasticity, and a gradual smoothing of fine lines and unevenness.
Because PDGF works by activating your body’s own repair mechanisms, results are layered and long-lasting, especially when integrated into a series of treatments or paired with regenerative modalities like microneedling, PRF, or broadband light.
The outcome is not an instant transformation, but a quietly powerful renewal - your skin, simply stronger.
Not quite. While PRP and PRF are derived from your own blood and contain a mix of platelets and plasma, Pure PDGF is a lab-refined, pharmaceutical-grade growth factor, specifically PDGF-BB. It offers consistent, sterile, and highly concentrated regenerative power without the variability of blood-based treatments.
No. One of the key benefits of Ariessence Pure PDGF is its precision and purity, it’s pre-formulated and sterile, meaning no blood draw is necessary. This makes it ideal for those seeking the benefits of regenerative therapy without the invasiveness of platelet-derived treatments.
At Petal + Stem, Pure PDGF is applied post-procedure when the skin is primed to absorb regenerative actives. It penetrates through microchannels to stimulate collagen, calm inflammation, and accelerate healing from within.
Yes. Pure PDGF is non-immunogenic and free of additives, making it exceptionally safe for sensitive, compromised, or rosacea-prone skin. Its anti-inflammatory properties often help reduce redness and support a stronger skin barrier over time.
While visible results can be seen after a single treatment, optimal outcomes often develop through a series of sessions. We typically recommend 2–3 treatments spaced 4–6 weeks apart, especially when used alongside microneedling or laser. Your personalized plan will be guided by your consultation with your provider.
(651) 504-6859
Mon/Tues/Wed/Fri: 9 AM - 5 PM
Thur: 11 AM - 7 PM
Sat: By special appointment request only
